- Sábato, Antonio
- Sacks, Michael
- Sagal, Katey
- Sager, Carole Bayer
- Saint, Eva Marie
- Sainte-Marie, Buffy
- Saldana, Theresa
- Salle, Eriq La
- Salt, Waldo
- Sanders, George
- Sandler, Adam
- Sanford, Isabel
- Sanger, Jonathan
- Santaolalla, Gustavo
- Sarandon, Chris
- Sarandon, Susan
- Sardi, Jan
- Sargent, Alvin
- Sarno, John
- Sarrazin, Michael
- Sarsgaard, Peter
- Savage, Fred
- Savalas, Telly
- Saxon, John
- Sayles, John
- Scacchi, Greta
- Scarborough, Skip
- Schaffner, Franklin J.
- Schallert, Edwin
- Scharf, Walter
- Schary, Dore
- Scheider, Roy
- Schell, Maximilian
- Schepisi, Fred
- Schifrin, Lalo
- Schildkraut, Joseph
- Schlesinger, Adam
- Schlesinger, John
- Schnabel, Julian
- Schneider, Bert
- Schneider, Romy
- Schrader, Paul
- Schram, Bitty
- Schreiber, Liev
- Schroder, Rick
- Schroeder, Barbet
- Schulman, Tom
- Schwartz, Bernard
- Schwartz, Teri
- Schwartz, Stephen
- Schwary, Ronald L.
- Schwarzenegger, Arnold
- Schweizer, Richard
- Scofield, Paul
- Scorsese, Martin
- Scott, Ann
- Scott, George C.
- Scott, Jane
- Scott, Ridley
- Seal
- Sears, Heather
- Seaton, George
- Seberg, Jean
- Sedgwick, Kyra
- Seezer, Maurice
- Segal, Erich
- Segal, George
- Seger, Bob
- Seinfeld, Jerry
- Seitz, John F.
- Sellecca, Connie
- Selleck, Tom
- Sellers, Peter
- Seltzer, Dov
- Sembello, Michael
- Serkis, Andy
- Serling, Rod
- Sevigny, Chloë
- Seymour, Jane
- Shaffer, Anthony
- Shaffer, Peter
- Shakira
- Shalhoub, Tony
- Shamberg, Michael
- Shandling, Garry
- Shanley, John Patrick
- Sharif, Omar
- Sharkey, Ray
- Sharpe, Karen
- Shatner, William
- Shaw, David
- Shaw, Robert
- Shaw, Sam
- Shaw, Victoria
- Sheen, Charlie
- Sheen, Martin
- Shenkman, Ben
- Shepard, Sam
- Shepherd, Cybill
- Sheridan, Jim
- Sheridan, Nicollette
- Sherman, Richard M.
- Sherman, Vincent
- Sherman, Robert B.
- Shields, Brooke
- Shigeta, James
- Shimada, Yoko
- Shire, Talia
- Shore, Dinah
- Shore, Howard
- Shue, Elisabeth
- Shyamalan, M. Night
- Sidibe, Gabourey
- Sidney, George
- Sidney, Sylvia
- Siegel, Sol C.
- Sigel, Barbara
- Signoret, Simone
- Sigurdsson, Sjón
- Siliotto, Carlo
- Silliphant, Sterling
- Silverstein, Shel
- Silverstone, Alicia
- Silvestri, Alan
- Simmons, Jean
- Simon, Carly
- Simon, Neil
- Simon, Paul
- Simon, S. Sylvan
- Sinatra, Frank
- Sinatra, Nancy
- Singleton, Charles
- Sinise, Gary
- Sirk, Douglas
- Sizemore, Tom
- Skala, Lilia
- Skall, William V.
- Skelton, Red
- Skerritt, Tom
- Skinner, Anita
- Slater, Glenn
- Smith, Arthur
- Smith, Bernard
- Smith, Irby
- Smith, Jaclyn
- Smith, Lane
- Smith, Maggie
- Smith, Will
- Smits, Jimmy
- Smyth, Patty
- Snodgress, Carrie
- Snow, Tom
- Snyder, Eddie
- Sobieski, Leelee
- Soderbergh, Steven
- Solo, Robert H.
- Solondz, Todd
- Somers, Suzanne
- Sommars, Julie
- Sommer, Elke
- Sondheim, Stephen
- Sordi, Alberto
- Sorkin, Aaron
- Sorvino, Mira
- Sothern, Ann
- Spacek, Sissy
- Spacey, Kevin
- Spade, David
- Spader, James
- Spencer, John
- Spencer, Octavia
- Spiegel, Sam
- Spielberg, Steven
- Springfield, Tom
- Springsteen, Bruce
- St. John, Jill
- Stallone, Sylvester
- Stallone, Frank
- Stamp, Terence
- Stander, Lionel
- Stanley, Kim
- Stanwyck, Barbara
- Stapleton, Jean
- Stapleton, Maureen
- Stark, Ray
- Staunton, Imelda
- Steele, Tommy
- Steele, Jeffrey
- Steenburgen, Mary
- Steiger, Rod
- Steiner, Max
- Stephens, Harvey
- Sterling, Jan
- Stevens, Andrew
- Stevens, George
- Stevens, Inger
- Stevens, Kay
- Stevens, Leith
- Stevens, Stella
- Stevens, Michael
- Stevenson, McLean
- Stewart, James
- Stewart, Patrick
- Stewart, David A
- Stigwood, Robert
- Stiles, Julia
- Sting
- Stockwell, Dean
- Stoltz, Eric
- Stone, Harold J.
- Stone, Milburn
- Stone, Oliver
- Stone, Sharon
- Stone, Emma
- Stonestreet, Eric
- Stowe, Madeleine
- Strasberg, Lee
- Strasberg, Susan
- Strathairn, David
- Strauss, Peter
- Streep, Meryl
- Street, Jody
- Streisand, Barbra
- Stricklyn, Ray
- Stringfield, Sherry
- Strode, Woody
- Stroheim, Erich von
- Struthers, Sally
- Stuart, Gloria
- Stuhlbarg, Michael
- Sturges, John
- Styne, Jule
- Styner, Jerry
- Sullivan, Ed
- Sullivan, Susan
- Sullivan III, Frankie
- Summer, Donna
- Surtees, Robert L.
- Susskind, David
- Sutherland, Donald
- Sutherland, Kiefer
- Suzman, Janet
- Swank, Hilary
- Swanson, Gloria
- Swayze, Patrick
- Swenson, Inga
- Swift, David
- Swinton, Tilda
- Swit, Loretta
- Sydow, Max von
- Szabó, István
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